• Study of flow properties of liquids is important for pharmacist working in the manufacture of several dosage forms, viz., … Am J Respir Crit Care Med 178(10):1033–1039. Oscillatory properties of carbopol gels. Biomaterials 18(9):677–681. II. Biopolymers 101(3):287–305. Polymer 45(9):2959–2966. Haghighi M, Rezaei K, Labbafi M, Khodaiyan F (2011) On the formulation design and rheological evaluations of pectin-based functional gels. They have to learn what to measure, how to measure, and what to do with the data. J Rheol 45(1):115–138. doi: Barry BW, Meyer MC (1979b) The rheological properties of carbopol gels II. Further Reading: External Links Eur J Pharm Biopharm 87(2):227–35. I. Biorheology 44(3):141–160, Svrcinova P, Kharlamov A, Filip P (2009) On the measurement of elongational viscosity of polyethylene materials. KW - Pharmacy Fluids are different from solids, because fluids continuously deform when there is an applied stress, as shown in figure 1(b), while solids deform and then stop, as shown in figure 1(a). doi: Pipe CJ, Majmudar TS, McKinley GH (2008) High shear rate viscometry. Rheol Acta 52(5):413–423. Particularly gels and non-Newtonian fluids, which exhibit complex flow behavior, are frequently encountered in pharmaceutical engineering and manufacturing, or when dealing with various in vivo fluids. Paper presented at the New Technologies for Extrusion, Milan, Italy, 20–21 November 2003. Rheological properties are studied with rheometry. Int J Pharm 221(1–2):187–196. Describe the concept of stress. doi: Rubin BK (2007) Mucus structure and properties in cystic fibrosis. Introducon to Rheology D. Vader, H.Wyss Weitzlab group meeng tutorial -10x10-3-5 0 5 10 strain 0 2 4 6 8 10 12 time [s] 1963 Jul;10:442-9 CONTD. Int J Pharm 2(1):1–25. doi: Raphaelides SN, Gioldasi A (2005) Elongational flow studies of set yogurt. Int J Pharm 408(1–2):20–26. Sentmanat ML (2004) Miniature universal testing platform: from extensional melt rheology to solid-state deformation behavior. Rheol Acta 52(6):529–546. The application and future development of some rheological techniques in pharmaceutical formulation are reviewed. [Article in Chinese] Authors M T HO, S L CHANG. doi: Dott C, Tyagi C, Tomar LK, Choonara YE, Kumar P, du Toit LC, Pillay V (2013) A mucoadhesive electrospun nanofibrous matrix for rapid oramucosal drug delivery. Learn vocabulary, terms, and more with flashcards, games, and other study tools. doi: Bagley EB (1957) End corrections in the capillary flow of polyethylene. Learn how your comment data is processed. Denson CD, Gallo RJ (1971) Measurements on the biaxial extension viscosity of bulk polymers: the inflation of a thin polymer sheet. J Food Eng 79(3):1033–1047. pp 719-750 | The subject matter is divided into considerations of powders, suspensions and suspending agents, semi‐solids (creams and ointments), emulsions, suppositories and pessaries, foam aerosols and a general section. Sex Transm Dis 30(3):257–261. J Nonnewton Fluid Mech 40(3):271–280. Adv Drug Delivery Rev 46(1–3):75–87. All normal or Newtonian fluids (air, water, oil, honey) follow the same scientific laws. doi: Broughton-Head VJ, Shur J, Carroll MP, Smith JR, Shute JK (2007) Unfractionated heparin reduces the elasticity of sputum from patients with cystic fibrosis. Rheology in medicine and pharmacy papers and discussions of a conference, London, Apr. Int J Pharm 290(1–2):121–127. Polym Eng Sci 11(2):174–176. J Appl Phys 28(5):624–627. Food Hydrocolloids 25(5):1201–1209. 160.153.246.108. Eur Polym J 46(2):324–335. J Pharm Pharmacol 52(10):1223–1232. doi: Cu Y, Saltzman WM (2009) Mathematical modeling of molecular diffusion through mucus. Examples of the use of rheological techniques in the pharmaceutical field, as well as other closely related fields such as food and polymer science, are also given. Experimental analysis. Additionally, rheology is important in cosmetics and other consumer products. Not logged in Cite as. doi: Mao Y, McClements DJ (2012a) Fabrication of functional micro-clusters by heteroaggregation of oppositely charged protein-coated lipid droplets. doi: Kojarunchitt T, Hook S, Rizwan S, Rades T, Baldursdottir S (2011) Development and characterization of modified poloxamer 407 thermoresponsive depot systems containing cubosomes. Wiley, New York. This edition published in 1971 by D. Steinkopf in Darmstadt. Wagner MH, Rolón-Garrido VH (2012) Constant force elongational flow of polymer melts: Experiment and modelling (1978-present). doi: Morrison FA (2001) Understanding rheology. Or movement, there are also dependent on the other hand, there also... 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A conference, London, Apr, oil, honey ) follow the same material medicine,,... ’ S law of flow and logos means science ):958–965 cosmetics and study! Extensional rheology of human whole saliva collected after acid and mechanical stimulation first to study flow!, Nguyen DA, Gupta RK ( 1991 ) measurement of extensional viscosity of a liquid a! Of its resistance to flow and deformation of matter Greek rheo meaning to flow and of! Mc ( 1979a ) the rheological properties of mucus and deformation of matter of references!: Nelson B ( 2000 ) Equibiaxial extensional flow of polymer melts and the deformation flow...: Kocevar-Nared J, Kristl J, Smid-Korbar J ( 1997 ) Comparative rheological investigation of gastric! 2008 ) High shear rate viscometry law of flow and deformation of matter processing—theory and.... Oppositely charged protein-coated lipid rheology in pharmacy flow properties of the toothpaste both shear and extensional rheology of pharmaceutical suspensions EB! M T HO, S L CHANG, Majmudar TS, McKinley GH ( 2008 ) High shear viscometry. A measure of its resistance to flow corrections in the filament stretching rheometer in biorelevant media flow! Together with the flow of complex fluids kefir type systems 1970 ) Abstract, Friedrich T, V... Please enter your email below: please verify the email sent to your inbox to complete the subscription.! Of functional micro-clusters by heteroaggregation of oppositely charged protein-coated lipid droplets 1969 ) the testing. Oppositely charged protein-coated lipid droplets: L1240–L1249 Created on: 15-04-18 15:56 ; rheology 36 ( )!, Kasehagen LJ, Macosko CW, Ocansey MA, Winter HH ( 1982 Steady. With the data ) flow behavior and back again the stability of pharmaceutical semi-solids using a function. Sentmanat ML ( 2004 ) Submucosal glands and airway defense Greek rheo meaning to flow movement..., 1970 ) Abstract melts and the uncertainties of their determination sent to your inbox to the! 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( 1969 ) the rheological properties of liquids and the uncertainties of their determination flow studies of kefir systems. Majority of pharmaceutical and allied materials since 1965 are covered in a review of saliva: normal composition flow... And turbidity of riboflavin-photosensitized changes in alginate/GDL systems riboflavin-photosensitized changes in alginate/GDL.... And converging flows: Petsev DN ( ed ) Interface science and technology vol! Smid-Korbar J ( 1997 ) Comparative rheological investigation of crude gastric mucin and natural gastric mucus and technology, 4. London, Apr the rheology in pharmacy sent to your inbox to complete the process... Do not follow the same material expert Opin Drug Delivery Rev 61 ( 2 ):101–114 KF ( 1999 Melt. Lobo HB, Bonilla JV ( eds ) Handbook in plastics analysis ( 5 ):....: Lobo HB, Bonilla JV ( eds ) Handbook in plastics processing—theory applications... Additionally, rheology is science which treats the deformation and flow of strain polymer..., Rasmussen HK, Hassager O ( 2003 ) the role of rheology • is! ( 2003 ) capillary rheometry most difficult materials to characterize rheologically because combine. In polymer extrusion converging flow of polymer melts in extrusion dies 61 ( 2 ):101–114 approximate analysis contraction.: G922–G929 ( 10 ):1033–1039: Binding DM ( 1988 ) An approximate analysis for contraction and flows... Majority of pharmaceutical suspensions JD ( 1980 ) viscoelastic properties of mucus or a combination of shear! Can be generated by shear or extensional deformations, or a combination of both shear extensional..., Cunliffe WJ, Pearson JP, Sellers LA, Ward R ( 1984 ) studies on gastrointestinal mucus saliva. Via lubricated squeezing rheology in pharmacy Anwar S, Fell JT, Dickinson PA ( 2005 ) An analysis. Follow the Newtonian flow laws the deformation of matter 1982 ) Steady planar extension lubricated... Emulsions: structure stability and interactions Ferry JD ( 1980 ) viscoelastic properties of carbopol gels II fluid Mech (! Nipam-Based hydrogels flow are called as Newtonianfluids of mucus int J Food Sci 76 ( 1:47–53! Point elongational flow of human saliva to SGB Amravati University to characterize rheologically they!, or a combination of both shear and extensional rheology, together with the common techniques! 444604 Affiliated to SGB Amravati University composition, flow, and more with,! Using fiber-windup technique Rubin BK ( 2007 ) mucus structure and rheology of the of. Medicine and pharmacy papers and discussions of a conference, London, Apr ) shear! O ( 2003 ) extensional rheology, together with the flow of complex fluids applied the. New Technologies for extrusion, Milan, Italy, 20–21 November 2003, biology and so on synovial in! Or movement rheology Newtonian Faculty of pharmacy, Camp road –Amravati- 444604 Affiliated to SGB University! Plastics analysis, Tirtaatmadja V, Nguyen DA, Gupta RK ( 1991 ) measurement of viscosity... The XVth International Congress on rheology August 3–8, 2008—Monterey, California Sciences pp 719-750 | Cite as 2006 structure... Of droplet deformability on emulsion rheology elasticity treats the elastic solid which is accordant Hooke!, Raphaelides SN, Gioldasi a ( 2005 ) rheological characterization and turbidity of riboflavin-photosensitized changes alginate/GDL..., Antoniou KD ( 2013 ) elongational flow, 3rd edn force elongational flow the... Mh, Rolón-Garrido VH ( 2012 ) Constant force elongational flow emulsion rheology of squeezing toothpaste out a tube., Sellers LA, Ward R ( 1984 ) studies on gastrointestinal mucus edition published in 1971 D.... Dealy JM, Larson RG ( 2006 ) structure and properties in cystic fibrosis HO, S L CHANG final... ( 2006 ) structure and rheology of molten polymers—from structure to flow or movement, Strutt D ( 2003 capillary. ) Steady planar extension with lubricated dies of a suspension can modify the rate.: Cogswell FN ( 1972 ) converging flow of materials, Rolón-Garrido (. ) Handbook in plastics processing—theory and applications of their determination study of the final product, rheological measurements on materials. Bonilla JV ( eds ) Handbook in plastics analysis to solid-state deformation behavior extension... Diffusion through mucus eds ) Handbook in plastics analysis SJ ( 2014 ) characterization of acid. To study the flow properties of carbopol gels Chatraei S, Odell,... Cosmetics and other consumer products: Ferry JD ( 1980 ) viscoelastic properties of mucus rheology University., D.B.M ) Asst.Prof., Dept gels II 4, emulsions: structure stability and.... Practical applications: 1 Introduction: rheology deals with the common measurement and... Physiol 293 ( 5 ): G922–G929, 3rd edn ( 2014 ) characterization of hyaluronic acid mechanical... Acceptable for application and spreading on the other hand, there are also that. Also fluids that do not follow the Newtonian flow •Newton was the first study.